---标题:“H. Integration分析”{H。综合分析}%\ vignetteengine {knitr :: Rarmmardown} \ usepackage [utf8] {inputenc} ---```范围和机会##案例研究1:TCGA拷贝数/表达#访问'Consortium'数据#表示集成数据集##密钥组件样本 - 包括在每个测定上测量的“表型”属性 - 通常,矩形功能x样本`矩阵()“值 - 不同的表示:`data.frame()的特征,样本,值元组。Experiments - Sample inputs to each experiment - Assay outputs from each experiment - Additional experiment-specific information, each date on which samples were processed ## Alternative Representations R-based representations Other approaches - Data base - 'Scientific' representations, e.g., [HDF5](http://www.hdfgroup.org/HDF5/) - 'Computational' representations, e.g., [HDFS](http://hadoop.apache.org/docs/r1.2.1/hdfs_design.html) ## A preliminary design # Statistical and other challenges # Practical