{r setup, echo=FALSE}库(LearnBioconductor) stopifnot(BiocInstaller::biocVersion() == "3.0")``` ```{r style, echo = FALSE, results = 'asis'}该包包含2014年秋季介绍性课程“序列分析学习r_ / _Bioconductor_”的培训材料，10月27-29日，华盛顿州西雅图。本课程是针对初学者和中级用户谁想要介绍分析和理解高通量序列数据使用_R_和_Bioconductor_。第一天主要学习基本的背景知识:介绍_R_编程语言;有效使用bioconductor软件的中心概念;并概述了高通量序列分析的工作流程。第2天强调使用_生物传导_用于特定的任务:RNA-seq差异表达工作流程;探索性、机器学习和其他统计任务;基因集富集; and annotation. Day 3 transitions to understanding effective approaches for managing larger challenges: strategies for working with large data, writing re-usable functions, developing reproducible reports and work flows, and visualizing results. The course combines lectures with extensive hands-on practicals; students are required to bring a laptop with wireless internet access and a modern version of the Chrome or Safari web browser. ## Schedule (tentative) Day 1: Learn _R_ / _Bioconductor_ - 9:00 - 10:30 [Introduction to _R_](A01.1_IntroductionToR.html): objects, functions, help! - 11:00 - 12:30 [Introduction to _Bioconductor_](A01.2_IntroductionToBioconductor.html): working with packages and classes - 1:30 - 5:00 (break: 3:00 - 3:30) [Introduction to sequence analysis](A01.3_BioconductorForSequenceAnalysis.html): typical work flow; data types and quality assessment; essential _Bioconductor_ packages Day 2: Use _R_ / _Bioconductor_ - 9:00 - 12:30 (break: 10:30 - 11:00) An RNA-seq differential expression work flow ([lecture](B02.1_RNASeq.html); [practical](B02.1.1_RNASeqLab.html)) - 1:30 - 2:00 [Other work flows](B02.2_CommonWorkFlows.html) (survey): ChIP-seq, variants, copy number, epigenomics - 2:00 - 3:00 [Machine learning](B02.3_MachineLearning.html); exploratory and other statistical analysis - 3:30 - 4:00 [Annotating genes, genomes, and variants](B02.4_Annotation.html) - 4:00 - 5:00 [Approaches to gene set enrichment](B02.5_GeneSetEnrichment.html) Day 3: Develop Skills and Best Practices - 9:00 - 10:30 [Working with large data](C03.1_LargeData.html) - 11:00 - 12:30 [Organizing code in functions, files, and packages](C03.2_CodeToPackages.html) - 1:30 - 3:00 [Reproducible reports and work flows](C03.3_ReproducibleResearch.html) - 3:30 - 4:30 [Visualization](C03.4_Visualization.html) - 4:30 - 5:00 Summary